butabarbital decreases results of sufentanil SL by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Closely. Coadministration of CYP3A4 inducers may possibly minimize sufentanil ranges and efficacy, potentially precipitating withdrawal syndrome in people that have designed Bodily dependence to sufentanil. Discontinuation of concomitantly made use of CYP3A4 inducers might boost sufentanil plasma concentration.

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butabarbital will decrease the level or impact of bazedoxifene/conjugated estrogens by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.

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butabarbital will decrease the level or effect of trazodone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.

butabarbital will minimize the extent or effect of fosamprenavir by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.

butabarbital will minimize the level or influence of tacrolimus by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.

butabarbital will lower the extent or influence of fruquintinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. If coadministration with reasonable CYP3A4 inducers is unavoidable, carry on to administer fruquintinib at proposed dosage.

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butabarbital will reduce the extent or influence of fesoterodine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.

butabarbital will lower the extent or outcome of norgestrel by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep an eye on Intently. Average CYP3A4 inducers might lower progestin focus; consider use of further barrier procedures

When merged use click here is needed, take into consideration minimizing doses of a number of medications. Usage of sodium oxybate with Liquor or sedative hypnotics is contraindicated. Consider therapy modification